Thermal-dilution technics.
نویسنده
چکیده
• .All thennal methods for the study of the circulation depend upon the induction of a change in the heat content of! the blood stream. As a result of the change, a particular time-dependent spatial distribution of temperature is developed in the blood according to the manner in which the change is brought about and as a function of the prevailing pattern of blood flow. In a general sense, any thermal method could be considered to involve thermal dilation, but, in keeping with the usual meaning of "indicator dilution," the term "thermal dilution" will be restricted to refer to those technics in which, following the artificial induction of a known change in the blood heat content at some point in the circulation, the resulting temperature change is followed at such a distance downstream that an even distribution of heat is presumed to have been developed over the whole vascular cross section. The induced change in heat content in a thermal-dilution technic may be either positive or negative, that is, heat is either added to or abstracted from the blood stream. One may speak, instead, of positive or negative heat addition in accordance with whether an increase or decrease in temperature is induced, but it is perhaps simpler and just as acceptable to refer to the addition of heat or cold. The change in the heat content of the blood may be achieved in several ways, for example by generation of heat within the blood itself (as is ideally the case in the diathermy-thermostromuhr of Eein), by conduction of heat across a vessel wall, by an intravaseular heating or cooling device, or by the injection into the blood stream of a mass miscible with the blood and at a different temperature. Thermal dilution using this last method of changing blood heat content most closely resembles other common indicator-dilution methods
منابع مشابه
Diagnostic applications of indicator-dilution technics in congenital heart disease.
Introduction • The diagnostic use of indicator-dilution technics in the study of congenital heart disease dates, for practical purposes, from 1950 with the nearly simultaneous description of methods for continuous recording of the concentration of Evans blue dye from Johns Hopkins University and from the Mayo Clinic." The diagnostic applications of indicatoi'-dilution technics have been intensi...
متن کاملThe Use of Ascorbate Dilution Curves
AT THE PRESENT time, indicator-dilution curves are one of the most important technics employed in the investigation of the circulation. The earliest of these studies were carried out by the rapid serial collections of blood samples and their subsequent photometric analysis.' This ingenious but cumbersome method was replaced by the continuous withdrawal of blood in front of a photoelectric cell,...
متن کاملIndicator-dilution studies with "diffusible" indicators.
• The indicator-dilution principle has been applied to studies of the circulation in order to provide estimates of flows and volumes in the vascular compartment. A sine qua non of validity of these estimates is that the indicator used remain within the confines of: the vascular compartment for the entire duration of the period required to obtain appropriate samples of blood. In such a symposium...
متن کاملUse of external counting technics in studies of the circulation.
• A number of new technics involving external detection of radioactivity in the blood stream or in tissues have been proposed as means for determining the rate, volume and pathway of blood flow in the intact subject. By virtue of their dependence on indirect, external measurement of indicator (isotope) activity in the body as opposed to direct measurement, these technics have been categorized a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Circulation research
دوره 10 شماره
صفحات -
تاریخ انتشار 1962